超分子配位化学研究所
Institute of Supramolecular Coordination Chemistry
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Self-Assembly of Copper Polypyridyl Supramolecular Metallopolymers to Achieve Enhanced Anticancer Efficacy

Lanhai Lai+, Dong Luo+, Ting Liu, Wenjie Zheng, Tianfeng Chen,* and Dan Li*[a]



AbstractSelf-assembled functional supramolecular metallopolymers have demonstrated application potential in cancer therapy. Herein, a copper polypyridyl complex was found able to selfassemble into a supramolecular metallopolymer driven by the intermolecular interactions, which could enhance the uptake in cancer cells through endocytosis, and thus effectively inhibiting tumor growth in vivo without damaging to the major organs. This study provides a facile way to achieve enhanced anticancer efficacy by using self-assembled metallopolymers.


文章链接:ChemistryOpen 2019 434.pdf